Pittsford is a town in Monroe County, New York, United States and is a semi-affluent suburb of Rochester. The population was 29,405 at the 2010 census.

The Town of Pittsford (formerly part of the town of Northfield) was incorporated in 1827. It was named by Colonel Caleb Hopkins, Pittsford's first town supervisor and War of 1812 hero, for the town of his birth, Pittsford, Vermont.

The Town of Pittsford is located in the southeastern portion of Monroe County approximately eight miles from the city of Rochester, New York. The Town of Mendon lies to the south, the Town of Perinton to the east, the Towns of Henrietta and Brighton to the west, and the Towns of Brighton and Penfield to the north.

The early history of the town is marked by the punitive Marquis Denonville expedition against the Seneca tribe in 1687.

In 1788, Massachusetts abandoned its claim to this region in favor of New York. The District of Northfield was formed in Ontario County in 1792, which became the Town of Northfield in 1796. As Northfield was subdivided in the following years, a final split formed the towns of Pittsford and Henrietta in 1814.